A bioinformatic survey of RNA-binding proteins in Plasmodium
نویسندگان
چکیده
منابع مشابه
RNA-binding proteins: a lesson in repression.
Regulation of protein expression in neurons by controlling not only when, but where, mRNAs are translated is likely to play an important role in neuronal function. In this review I focus on the mRNA-binding proteins that control mRNA translation in neurons and how they may participate in local, synaptodendritic protein synthesis.
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More than 200 phosphorylated 14-3-3-binding sites in the literature were analysed to define 14-3-3 specificities, identify relevant protein kinases, and give insights into how cellular 14-3-3/phosphoprotein networks work. Mode I RXX(pS/pT)XP motifs dominate, although the +2 proline residue occurs in less than half, and LX(R/K)SX(pS/pT)XP is prominent in plant 14-3-3-binding sites. Proline at +1...
متن کاملRNA-binding proteins in trypanosomes
Background: Trypanosomes mostly control gene expression by post-transcriptional events such as modulation of mRNA stability and translational efficiency. These mechanisms involve RNAbinding proteins (RBPs), which associate with transcripts to form messenger ribonucleoprotein (mRNP) complexes. Results: In this study, we report the identification of mRNA targets for Trypanosoma cruzi U-rich RBP 1...
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ژورنال
عنوان ژورنال: BMC Genomics
سال: 2015
ISSN: 1471-2164
DOI: 10.1186/s12864-015-2092-1